CAS 100-00-5: 1-Chloro-4-nitrobenzene

4-Chloronitrobenzene

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications 4-Chloronitrobenzene is a common intermediate in the production of a number of industrially useful compounds. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Guo, H.C., et al.: J. Am. Chem. Soc., 131, 6318 (2009); Miura, Y., et al.: J. Org. Chem., 59, 3294 (1994);

4-Chloronitrobenzene is a type strain of the bacterium Nitrosomonas europaea. It has been shown to be toxic to cells in both aerobic and anaerobic culture. 4-Chloronitrobenzene inhibits the activity of hydrogenase enzymes, which are required for the reduction of molecular oxygen to water. The toxicity of 4-chloronitrobenzene is due to its ability to inhibit enzyme activity, leading to cell death. This bacterium also has the ability to use chlorinated hydrocarbons as a carbon source and cause chlorination of other biological molecules. In addition, it can reduce metal hydroxides and form metal complexes with palladium and platinum metals. 4-Chloronitrobenzene is found in soil samples that have high concentrations of chloride ions or neutral pH values. Its phase equilibrium diagram shows that this compound exists mainly in liquid form when it is at low temperature, but becomes more

1-Chloro-4-nitrobenzene is an important intermediate used in the preparation of 2,4-dinitrochlorobenzene and 3,4-dichloronitrobenzene. It is used as a raw material in the preparation of 4-nitrodiphenylamine, 4-chloroaninline and (4-[(4-aminobenzene)sulfonyl]aniline). It serves as a common antioxidant, which is found in rubber. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.