CAS 100-19-6: p-Nitroacetophenone

4-Nitroacetophenone is an organic compound that has been synthesized in an asymmetric synthesis. It is a nitro compound and a radiosensitizer. The chemical structure of 4-Nitroacetophenone is similar to the structure of phenol, with one nitro group and two hydroxyl groups at opposite ends of the molecule. 4-Nitroacetophenone reacts with radiation to produce free radicals that can damage DNA, RNA, and proteins. The reaction mechanism involves the formation of nitrosating agent (R−NO) which interacts with DNA to form a covalent bond between the DNA base and the nitrosating agent. This covalent bond inhibits DNA replication, leading to cell death. 4-Nitroacetophenone has been shown to be effective in inhibiting cell growth in culture by triggering apoptosis in cells treated with high doses of this drug.

4'-Nitroacetophenone

4'-Nitroacetophenone is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.