CAS 1000-50-6: Butyldimethylsilyl chloride

N-Butyldimethylchlorosilane

Alkyl Silane - Conventional Surface Bonding Aliphatic, fluorinated aliphatic or substituted aromatic hydrocarbon substituents are the hydrophobic entities which enable silanes to induce surface hydrophobicity. The organic substitution of the silane must be non-polar. The hydrophobic effect of the organic substitution can be related to the free energy of transfer of hydrocarbon molecules from an aqueous phase to a homogeneous hydrocarbon phase. A successful hydrophobic coating must eliminate or mitigate hydrogen bonding and shield polar surfaces from interaction with water by creating a non-polar interphase. Although silane and silicone derived coatings are in general the most hydrophobic, they maintain a high degree of permeability to water vapor. This allows coatings to breathe and reduce deterioration at the coating interface associated with entrapped water. Since ions are not transported through non-polar silane and silicone coatings, they offer protection to composite structures ranging from pigmented coatings to rebar reinforced concrete. A selection guide for hydrophobic silanes can be found on pages 22-31 of the Hydrophobicity, Hydrophilicity and Silane Surface Modification brochure. n-Butyldimethylchlorosilane; Butylchlorodimethylsilane; Butyldimethylsilyl chloride; Chlorodimethyl-n-butylsilane Forms bonded phases for HPLC

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Butylchlorodimethylsilane is a chlorine atom that has inhibitory properties. It has been shown to inhibit the activity of proteases, which are enzymes in the body that digest proteins. Butylchlorodimethylsilane can be used as an inhibitor in a liquid chromatography method to separate proteins. The compound is also stable to hydrochloric acid and trifluoroacetic acid, making it suitable for use with quinolizine, which is sensitive to these chemicals.