CAS 100007-54-3: 3',4'-dihydroxyetoposide
Formula:C35H38O15
InChI:InChI=1/C29H32O13.C6H6O2/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3;7-5-3-1-2-4-6(5)8/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3;1-4,7-8H/t11-,15?,20-,21-,22+,24-,25-,26?,27-,29+;/m1./s1
Synonyms:- 3',4'-Dihydroxy-VP 16-213
- Dhvp-16-213
- Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5-(3,4-dihydroxy-5-methoxyphenyl)-9-((4,6-O-ethylidene-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-, (5R-(5alpha,5abeta,8aalpha,9beta(R*)))-
- (5S,5aR,8aR,9R)-9-(3,4-dihydroxy-5-methoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside
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Found 3 products.
3’-O-Desmethyl Etoposide
CAS:Controlled ProductApplications An Etoposide (E933750) metabolite References Relling, M., et al.: Mol. Pharmacol., 45, 352 (1994), Lovett, B., et al.: Biochem., 40, 1159 (2001), Zhuo, X., et al.: Drug Metab. Disposition, 32, 993 (2004), Fan, Y., et al.: Chem. Res. Toxicol., 19, 937 (2006),Formula:C28H30O13Color and Shape:NeatMolecular weight:574.533',4'-Dihydroxyetoposide
CAS:3',4'-Dihydroxyetoposide is an anti-cancer agent that belongs to the group of epipodophyllotoxins. It inhibits DNA synthesis and cell division by binding to topoisomerase II, leading to DNA breakage and the formation of single-stranded breaks. 3',4'-Dihydroxyetoposide has been shown to be safe for use in children with leukemia, although it is not active against cells without a nucleus, such as erythrocytes. This drug also has significant inhibition of human cytochrome P450 3A4 (CYP3A4) and human liver microsomes.Formula:C28H30O13Purity:Min. 95%Molecular weight:574.53 g/molRef: 3D-FD21267
Discontinued product3’-O-Desmethyl Etoposide-d4 (~ 90%)
CAS:Controlled ProductApplications 3’-O-Desmethyl Etoposide-d4, is the labeled analogue of 3’-O-Desmethyl Etoposide (D291970); which is an Etoposide (E933750) metabolite. References Relling, M., et al.: Mol. Pharmacol., 45, 352 (1994), Lovett, B., et al.: Biochem., 40, 1159 (2001), Zhuo, X., et al.: Drug Metab. Disposition, 32, 993 (2004), Fan, Y., et al.: Chem. Res. Toxicol., 19, 937 (2006),Formula:C28D4H26O13Purity:~90%Color and Shape:Light BrownMolecular weight:578.555
