
CAS 1000578-26-6: (2S)-1,2,3,4-Tetrahydro-N,N-dimethyl-5-(1,3,5-trimethyl-1H-pyrazol-4-yl)-2-naphthalenamine
Formula:C18H25N3
InChI:InChI=1S/C18H25N3/c1-12-18(13(2)21(5)19-12)17-8-6-7-14-11-15(20(3)4)9-10-16(14)17/h6-8,15H,9-11H2,1-5H3/t15-/m0/s1
InChI key:InChIKey=BTTOYOKCLDAHHO-HNNXBMFYSA-N
SMILES:CC1=C(C2=C3C(C[C@@H](N(C)C)CC3)=CC=C2)C(C)=NN1C
Synonyms:- 2-Naphthalenamine, 1,2,3,4-tetrahydro-N,N-dimethyl-5-(1,3,5-trimethyl-1H-pyrazol-4-yl)-, (2S)-
- AS 19
- (2S)-1,2,3,4-Tetrahydro-N,N-dimethyl-5-(1,3,5-trimethyl-1H-pyrazol-4-yl)-2-naphthalenamine
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AS 19
CAS:AS 19 is a potent antimicrobial agent that belongs to the class of 5-hydroxytryptamine receptor agonists. It has been shown to inhibit the growth of bacterial strains in vitro, including methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium. AS 19 is also active against Escherichia coli, Salmonella enterica serovar Typhimurium, Mycobacterium tuberculosis and Mycobacterium avium complex. This drug has been shown to be a potent inhibitor of neuronal death in rats. The mechanism of action is not yet clear; however, it may be due to the inhibition of 5-ht7 receptors on neurons or an anti-inflammatory effect. AS 19 inhibits locomotor activity at low doses and induces locomotor activity at high doses in mice.Formula:C18H25N3Purity:Min. 95%Molecular weight:283.41 g/molAS19
CAS:AS19 is a potent, selective 5-HT7 receptor agonist (IC50: 0.83 nM; Ki: 0.6 nM).Formula:C18H25N3Purity:98%Color and Shape:SolidMolecular weight:283.41