1-(3,4,5-trihydroxyphenyl)nonan-1-one, also known by its CAS number 100079-26-3, is an organic compound characterized by a nonanone backbone with a phenolic substituent. This compound features a long aliphatic chain (nonane) attached to a ketone functional group at one end and a phenolic group with three hydroxyl (-OH) groups at the 3, 4, and 5 positions on the aromatic ring. The presence of multiple hydroxyl groups contributes to its potential solubility in polar solvents and may enhance its reactivity in various chemical reactions, including oxidation and esterification. The phenolic structure suggests potential antioxidant properties, which could be of interest in biochemical applications. Additionally, the compound may exhibit biological activity, making it relevant in fields such as medicinal chemistry and natural product research. Its physical properties, such as melting point, boiling point, and solubility, would depend on the specific molecular interactions and the environment in which it is studied.

1-(3,4,5-trihydroxyphenyl)nonan-1-one

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THPN is a Nur77 agonist. It also induces autophagy in melanoma cell lines.

THPN

1-(3,4,5-Trihydroxyphenyl)-1-Nonanone

THPN is a new drug that has been shown to be effective in the treatment of metabolic disorders, such as type 2 diabetes. It has also been shown to have anti-inflammatory effects and may be useful for the treatment of autoimmune diseases. THPN is a metabolite of the drug phenformin, which is used to treat diabetes by increasing insulin sensitivity. THPN binds to nuclear dna and induces apoptosis in cancer cells. This drug also interacts with transcriptional regulators and can bind to response elements on DNA. The phase transition temperature for THPN is around -77°C.

CAS 100079-26-3: 1-(3,4,5-trihydroxyphenyl)nonan-1-one

THPN

Ref: TM-T24880

THPN

Ref: IN-DA01ENI9

1-(3,4,5-Trihydroxyphenyl)-1-Nonanone

Ref: 54-OR1023261

THPN

Ref: 3D-AEA07926