(R)-(+)-2-Bromopropionic acid is a chiral organic compound characterized by the presence of a bromine atom and a carboxylic acid functional group attached to a three-carbon chain. As a derivative of propionic acid, it features a bromine substituent at the second carbon, which imparts unique reactivity and properties. This compound exists as a colorless to pale yellow liquid or solid, depending on temperature and purity. It is soluble in polar solvents such as water and alcohols, owing to its carboxylic acid group. The presence of the bromine atom enhances its electrophilic character, making it useful in various organic synthesis reactions, particularly in the formation of chiral intermediates. Additionally, (R)-(+)-2-Bromopropionic acid is of interest in pharmaceutical chemistry due to its potential applications in the synthesis of biologically active compounds. Its chirality is significant in determining the compound's interactions in biological systems, influencing its pharmacological properties. Safety precautions should be taken when handling this compound, as it may pose health risks if ingested or inhaled.

(R)-(+)-2-Bromopropionic acid

10009-70-8: Propanoic Acid, 2-Bromo-, (2R)-, 2-R-(+) bromopropionic acid, (2R)-2-bromopropanoic acid

(R)-(+)-2-Bromopropionic acid is an isostere that can be used as a synthetic replacement for the naturally occurring amino acid D-alanine. It has been shown to have a high affinity for binding with peptide bonds and therefore has potential use in the synthesis of peptidomimetics. The compound was prepared by reacting 2-bromoacetic acid with (+) -L-valine in the presence of an acid catalyst. This reaction yielded (R)-(+)-2-bromopropionic acid, which then underwent esterification with d-alanine to form (R)-(+)-2-(d-alaninomethyl)propionic acid, a surrogate of D-alanine.

CAS 10009-70-8: (R)-(+)-2-Bromopropionic acid

(R)-(+)-2-Bromopropionic acid

Ref: 3D-FB60099

Propanoic acid, 2-bromo-, (2R)-

Ref: IN-DA0000W3

(R)-(+)-2-Bromopropionic acid

Ref: 54-OR471636

(R)-(+)-2-Bromopropionic Acid

Ref: 3B-B1756

(R)-(+)-2-Bromopropionic acid

Ref: 10-F097800