(+)-Mandelonitrile, with the CAS number 10020-96-9, is an organic compound characterized by its cyanohydrin structure, which features a hydroxyl group (-OH) and a nitrile group (-CN) attached to a benzene ring. This compound is typically a colorless to pale yellow liquid with a characteristic almond-like odor, reflecting its relation to mandelic acid. It is soluble in water and organic solvents, making it versatile in various chemical applications. (+)-Mandelonitrile is known for its role in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. The compound exhibits chiral properties, with the (+) designation indicating its specific optical activity. It is important to handle this substance with care, as it can be toxic and may pose health risks upon exposure. Additionally, its reactivity allows it to participate in various chemical reactions, including nucleophilic additions and condensation reactions, making it a valuable intermediate in synthetic organic chemistry.

(+)-Mandelonitrile

10020-96-9: (+)-(αR)-α-Hydroxybenzeneacetonitrile, (+)-Mandelonitrile, (+)-α-Mandelonitrile, (2R)-hydroxy(phenyl)ethanenitrile, (R)-(+)-2-Hydroxy-2-(phenyl)acetonitrile, (R)-2-Hydroxy-2-phenylacetonitrile, (R)-Hydroxy(phenyl)acetonitrile, (R)-α-Cyanobenzyl alcohol, (R)-α-Hydroxybenzeneacetonitrile, Benzeneacetonitrile, α-hydroxy-, (R)-, Benzeneacetonitrile, α-hydroxy-, (αR)-, (R)-Mandelonitrile, R-(+)-Mandelonitrile,  R-(+)-Mandelonitrile

Mandelonitrile is a phenylpropene with the chemical formula C7H6O2. It has an acidic ph and is soluble in water. Mandelonitrile is also a component of amygdalus, which is used in the production of almond oil. Mandelonitrile can be synthesized by reacting sodium citrate with trifluoromethanesulfonic acid and dry mandelic acid in a flow system. This process produces mandelonitrile as an intermediate, which can then be converted to (+)-mandelic acid by hydrogenation with Raney nickel catalyst. The kinetic and thermodynamic properties of this reaction have been studied using a model system that consists of an asymmetric synthesis.

CAS 10020-96-9: (+)-Mandelonitrile

(R)-(+)-Mandelonitrile

Ref: 3D-FM71455

(R)-(+)-Mandelonitrile

Ref: 4Z-M-257001

d-mandelonitrile

Ref: TM-T9158

Benzeneacetonitrile, α-hydroxy-, (αR)-

Ref: IN-DA000196