CAS: 1002101-19-0

Fezagepras

2-(3-Pentylphenyl)acetic acid is a synthetic fatty acid that has been shown to have potent activity in the treatment of chronic kidney disease. It inhibits the production of proinflammatory cytokines and growth factors, leading to decreased inflammation and fibrosis in the kidneys. This compound also prevents insulin resistance, which may be due to its ability to activate insulin receptors. 2-(3-Pentylphenyl)acetic acid is a crystalline polymorph with an activated carbon atom at position C-2 that can undergo conversion into other crystalline forms. The different morphs are distinguished by their physical properties and chemical reactivity.

Fezagepras (Setogepram) is an orally active GPR40 agonist and is an antagonist or inverse agonist of GPR84 with anti-inflammatory, anti-fibrotic, and anti-