CAS: 1003576-00-8

6-(2,2,2-Trifluoroethoxy)-N-[2-[[[1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl]amino]ethyl]nicotinamide is a potent inhibitor of adipose tissue lipolysis. It blocks the release of fatty acids from adipose tissue by inhibiting the phosphodiesterase enzyme that breaks down cyclic AMP (cAMP), an important second messenger in cells. 6-(2,2,2-Trifluoroethoxy)-N-[2-[[[1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl]amino]ethyl]nicotinamide blocks the release of fatty acids from adipose tissue and reduces body weight gain in animals. The molecule has been shown to have potent inhibitory activity against inhibitors of