CAS 1010-93-1: 2-Methyl-5-nitroimidazole-1-acetic acid

Applications 2-Methyl-5-nitroimidazole-1-acetic Acid is a metabolite of metronidazole with mutagenic activity. References Chacko, M., et al.: Indian J. Exp. Biol., 25, 240 (1987)

2-(2-Methyl-5-nitro-1H-imidazol-1-yl)acetic acid is an antimicrobial agent that inhibits the growth of bacteria by oxidation. It has been shown to be effective against protozoan parasites and has a good activity against Gram-positive bacteria. The main metabolic pathway for 2-(2-Methyl-5-nitro-1H-imidazol-1-yl)acetic acid is hydrolysis by hydrochloric acid, with a minor route involving hydroxy metabolite formation. This drug also acts as a prodrug for antipyrine, which inhibits bacterial growth via inhibition of protein synthesis.

Metronidazole acetic acid, a mutagenic metabolite of an antibiotic, targets protozoa and anaerobic bacteria.

Compounds containing an unfused imidazole ring, whether or not hydrogenated, in the structure, nesoi