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Sappanone A is a high isoflavanone with anti-inflammatory properties.Sappanone A reduces allergic airway inflammation in ovalbumin-induced asthma.

Sappanone A is a natural compound, which is derived from the heartwood of Caesalpinia sappan, a plant commonly found in regions of Southeast Asia. This flavonoid exhibits various biological activities, primarily attributed to its antioxidant and anti-inflammatory properties. Sappanone A acts by modulating cellular pathways involved in oxidative stress and inflammation, effectively scavenging free radicals and reducing inflammatory mediator production. The uses and applications of Sappanone A are extensive in medical and pharmaceutical research. It has been studied for its potential therapeutic effects in treating conditions such as cardiovascular diseases, neurodegenerative disorders, and certain types of cancer. Its ability to mitigate oxidative stress and inflammation makes it a promising candidate for developing novel therapeutic agents. Additionally, its natural origin and bioactivity profile make it of particular interest in the development of phytochemicals and nutraceuticals. Its versatility in modulating critical biological pathways underscores the significant potential of Sappanone A in enhancing human health and advancing therapeutic strategies.

Sappanone A

Applications Sappanone A is a natural product flavonoid with some antioxidant properties that can be isolated from C. sappan. References Namikoshi, M., et al.: Chem. Pharm. Bull., 35, 2761 (1987); Foroumadi, A., et al.: Bioorg. Med. Chem. Lett., 17, 6764 (2007);