5-Carboxyoxindole is an organic compound characterized by its oxindole structure, which features a bicyclic framework consisting of a benzene ring fused to a pyrrolidine ring. The presence of a carboxylic acid group at the 5-position of the oxindole moiety imparts distinct chemical properties, including acidity and the potential for hydrogen bonding. This compound is typically a white to off-white solid and is soluble in polar solvents, which is indicative of its functional groups. 5-Carboxyoxindole is of interest in various fields, including medicinal chemistry, due to its potential biological activities, such as anti-inflammatory and anticancer properties. Its reactivity can be influenced by the carboxylic acid group, allowing for further derivatization and synthesis of more complex molecules. Additionally, it may participate in various chemical reactions, including esterification and amidation, making it a versatile intermediate in organic synthesis. Overall, 5-Carboxyoxindole serves as a valuable compound for research and development in pharmaceuticals and related areas.

5-Carboxyoxindole

102359-00-2: 2-Oxoindoline-5-Carboxylic Acid, 2-oxo-2,3-dihydro-1H-indole-5-carboxylic acid, 2-oxo-2,3-dihydro-1H-indole-5-carboxylate, 2-Indolinone-5-carboxylic acid

2-Oxoindoline-5-carboxylic acid

2-Oxindole-5-carboxylic acid

1H-Indole-5-carboxylic acid, 2,3-dihydro-2-oxo-

5-Carboxyoxindole is a synthetic compound that has been shown to be cytotoxic in vitro and in vivo. It has been found to bind to the DNA of cancer cells, preventing DNA synthesis and replication, resulting in cell death. The mechanism of 5-carboxyoxindole is not completely understood but it has been suggested that it inhibits the production of ATP, leading to cell death. Techniques used to synthesize this compound include multistep reactions with yields up to 69%. These reactions are typically carried out at room temperature, although they can also be performed under reflux or microwave conditions.

CAS 102359-00-2: 5-Carboxyoxindole

2-Oxoindoline-5-carboxylic acid

Ref: 10-F236745

2-Oxindole-5-carboxylic acid

Ref: 54-OR10403

1H-Indole-5-carboxylic acid, 2,3-dihydro-2-oxo-

Ref: IN-DA00078Z

5-Carboxyoxindole

Ref: 3D-CEA35900