CAS 102839-00-9: 4-Quinazolinamine, 2,2'-(1,4-piperazinediyl)bis[6,7-dimethoxy-

2,2'-(1,4-Piperazinediyl)bis[6,7-dimethoxy-4-quinazolinamine] is a chemical compound that is used as a lead to develop new drugs against malaria. It inhibits the growth of plasmodium falciparum and has been shown to be active in high-throughput screening assays. 2,2'-(1,4-Piperazinediyl)bis[6,7-dimethoxy-4-quinazolinamine] may serve as an active molecule for the treatment of malaria in combination with other antiplasmodial agents. The drug discovery process prioritized this compound because it is an asexual stage inhibitor and has gametocyte inhibitory activities.

Impurity Terazosin EP Impurity E Stability Light Sensitive Applications 2,2'-(1,4-Piperazinediyl)bis[6,7-dimethoxy-4-quinazolinamine] (Terazosin EP Impurity E) is an impurity of selective alpha 1 antagonists: Terazosin (T105000) and Prazosin (P702325). References Feretti, R. et al.: J. Chrom. A, 1216, 5385 (2009); Bachman, W.J.: J. Liq. Chrom., 9, 1033 (1986);