CAS 10285-07-1: (+)-Lycopsamine

Applications (+)-Lycopsamine Hydrochloride, occurs in pyrrolizidine alkaloid-containing plants, which are the most common poisonous plants affecting livestock, wildlife, and humans. Thye are being known as hepatotoxins and tumorigens.It has been shown that pyrrolizidine Alkaloid-Derived DNA Adducts, are the common biological biomarker of pyrrolizidine alkaloid-induced liver tumor formation. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Qingsu, X., et al.: Chem. Res. Toxic., 26, 1384 (2013); Bosi,, C. F., et al.: Revista Brasileira de Farmacognosia, 23, 425 (2013);

Natural alkaloid

Lycopsamine is a bioactive chemical.

Lycopsamine is a pyrrolizidine alkaloid, which is a naturally occurring compound found in several plant species, particularly those within the Boraginaceae family. These alkaloids are primarily sourced from plants known for producing secondary metabolites as a defense mechanism against herbivores and pathogens. Lycopsamine's mode of action involves its biotransformation in the liver where it forms reactive metabolites that can bind to cellular macromolecules. This results in hepatotoxicity, disrupting liver function and potentially leading to conditions such as veno-occlusive disease. In scientific research, lycopsamine is studied for its implications in plant biochemistry, toxicology, and environmental health. Its presence in medicinal plants or contaminated food products raises concerns about human and animal health, necessitating analytical methods for detection and quantification. Understanding the pathways of lycopsamine and related alkaloids can also contribute to insights into plant-insect interactions and ecological dynamics. Furthermore, researchers explore detoxification methods to mitigate its toxic effects in both agricultural and clinical settings, providing a comprehensive approach to managing its presence in the environment.