CAS 10302-78-0: 2',3',5'-Triacetyl-azacytidine
Formula:C14H18N4O8
InChI:InChI=1/C14H18N4O8/c1-6(19)23-4-9-10(24-7(2)20)11(25-8(3)21)12(26-9)18-5-16-13(15)17-14(18)22/h5,9-12H,4H2,1-3H3,(H2,15,17,22)
SMILES:CC(=O)OCC1C(C(C(n2cnc(=N)nc2O)O1)OC(=O)C)OC(=O)C
Synonyms:- 4-amino-1-(2,3,5-tri-O-acetylpentofuranosyl)-1,3,5-triazin-2(1H)-one
- 1,3,5-Triazin-2(1H)-one, 4-amino-1-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)-
- 2',3',5'-triacetyl-5-Azacytosine
- 2'',3'',5''-Triacetyl -Azacytidine
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Found 9 products.
Azacitidine Triacetate
CAS:Formula:C14H18N4O8Color and Shape:White To Off-White SolidMolecular weight:370.325-Azacytidine 2’,3’5’-O-triacetate
CAS:Applications 5-Azacytidine 2’,3’5’-O-triacetate is a useful compound for the treatment and prevention of cancer and disorders related to abnormal cell proliferation, hematological disorders, and myelodysplastic syndromes (MDS). It can be also used to synthesize 2'3'5'triacetyl-5-azacytidine which is a prodrug for azacitidine. Azacitidine is a FDA-appproved DNA metnyltransferase (DNMT) inhibitor. References Rajendiran, C., et al.: PCT Int. Appl. WO 2012135405 A1 20121004 (2012); Ziemba, A., et al.: Chemother Res Pract 965826, 9 (2011); Beisler, J. A., et al.: J. Carbohyd. Chem 4, 281 (1977)Formula:C14H18N4O8Color and Shape:White To Off-WhiteMolecular weight:370.312',3',5'-Triacetyl -azacytidine
CAS:2',3',5'-Triacetyl-azacytidine is a transcription factor that has dose-dependent effects on the production of melanin. It inhibits the synthesis of melanin by binding to two specific transcription factors, the microphthalmia-associated transcription factor and the histone methyltransferases. This drug also inhibits tyrosinase, which is an enzyme involved in the production of melanin. 2',3',5'-Triacetyl-azacytidine has been shown to inhibit the growth of murine melanoma cells and may be useful for treating skin cancer.Formula:C14H18N4O8Purity:Min. 95%Molecular weight:370.31 g/mol2',3',5'-triacetyl-5-Azacytidine
CAS:2',3',5'-triacetyl-5-Azacytidine (Nsc291930) is a prodrug form of 5-azacytidine that may be rapidly absorbed orally.Formula:C14H18N4O8Purity:98.34%Color and Shape:SolidMolecular weight:370.31Ref: TM-T7840
2mg40.00€5mg52.00€10mg80.00€25mg129.00€50mg187.00€100mg281.00€200mg406.00€1mL*10mM (DMSO)64.00€2',3',5'-triacetyl-5-Azacytidine
CAS:2',3',5'-triacetyl-5-AzacytidinePurity:≥98%Molecular weight:370.31g/mol
