o-Toluic acid, 5-acetamido- (6CI), with the CAS number 103204-70-2, is an organic compound characterized by the presence of both a toluic acid moiety and an acetamido group. This compound features a benzene ring substituted with a carboxylic acid group (–COOH) and an acetamido group (–NHCOCH3) at the ortho position relative to each other. The presence of these functional groups imparts specific chemical properties, such as acidity due to the carboxylic acid and potential for hydrogen bonding from the acetamido group. The compound is likely to exhibit moderate solubility in polar solvents due to its ability to form hydrogen bonds. Additionally, it may participate in various chemical reactions typical of carboxylic acids and amides, including esterification and amidation. Its structural characteristics suggest potential applications in pharmaceuticals or as an intermediate in organic synthesis. As with many organic compounds, safety and handling precautions should be observed due to potential toxicity or reactivity.

o-Toluic acid, 5-acetamido- (6CI)

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5-Acetamido-2-methylbenzoic acid is a linker that is used to attach ubiquitin to other proteins as a covalent inhibitor. It has been shown to inhibit the HIV-1 reverse transcriptase, which is an enzyme in the viral replication process. 5-Acetamido-2-methylbenzoic acid is also able to form a covalent bond with peptidomimetic warheads, which are compounds that mimic viral proteins and inhibit the activity of host immune response enzymes. This compound has been shown to be reactive with polymerases, such as RNA polymerase and DNA polymerase, inhibiting their activity.

CAS 103204-70-2: o-Toluic acid, 5-acetamido- (6CI)

5-Acetamido-2-methylbenzoic acid

Ref: 3D-DEA20470

5-Acetamido-2-methylbenzoic acid

Ref: 10-F637679