CAS 10321-49-0: 4-bromoisoquinolin-3-amine

4-Bromo-isoquinolin-3-ylamine is a compound that belongs to the class of isoquinoline derivatives. It is used in organic synthesis for cyclization, iodination, and cross-coupling reactions. In particular, it has been shown to be effective for the synthesis of acetylenes and condensed tricyclic skeletons. 4-Bromo-isoquinolin-3-ylamine can be used as an intermediate in the synthesis of aryl halides or methyl esters by reaction with an electrophile. It can also be used to synthesize compounds containing acetaldehyde or fluoride. The buchwald reaction between 4-bromo-isoquinolin-3-ylamine and chloromethyl methyl ether gives 2-(chloromethyl)isoquinoline, which can undergo further transformations to give substituted quinolines.

4-Bromoisoquinolin-3-amine