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CAS 103476-89-7: L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-formylbutyl]-, sulfate (2:1)
Formula:C20H38N6O4H2O4S
InChI:InChI=1S/C20H38N6O4.H2O4S/c1-12(2)9-16(24-14(5)28)19(30)26-17(10-13(3)4)18(29)25-15(11-27)7-6-8-23-20(21)22;1-5(2,3)4/h11-13,15-17H,6-10H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H4,21,22,23);(H2,1,2,3,4)/t15-,16-,17-;/m0./s1
InChI key:InChIKey=IBDASEYBOOUHFZ-FRKSIBALSA-N
SMILES:[C@@H](NC([C@H](CC(C)C)NC(C)=O)=O)(C(N[C@@H](CCCNC(=N)N)C=O)=O)CC(C)C.S(=O)(=O)(O)O
Synonyms:- (2S)-2-(acetylamino)-N-[(2S)-2-({4-[(diaminomethylidene)amino]-1-formylbutyl}amino)-4-methylpentanoyl]-4-methylpentanamide (non-preferred name)
- 2-(2-Acetamido-4-methylvaleramido)-N-(1-formyl-4-guanidinobutyl)-4-methylvaleramide
- <span class="text-smallcaps">L</smallcap>-Leucinamide, N-acetyl-<smallcap>L</span>-leucyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-formylbutyl]-, sulfate (2:1)
- <span class="text-smallcaps">L</smallcap>-Leucinamide, N-acetyl-<smallcap>L</span>-leucyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, (S)-, sulfate (2:1)
- Acetyl-L-leucyl-L-leucylargininal
- L-Leucinamide, N-acetyl-L-leucyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)-
- Leupeptin Ac-LL
- Leupeptin Hemisulfate From Microbial*Source
- Leupeptin hemisulfate
- N-Acetyl-L-leucyl-L-leucyl-L-argininal
- N-acetyl-L-leucyl-N-{(2S)-5-[(diaminomethylidene)amino]-1-oxopentan-2-yl}-L-leucinamide
- See more synonyms
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Leupeptin
CAS:A reversible compeptitive protease inhibitor, which was shown to inhibit cathepsins B, H, L, and S, calpain and trypsin. Ac-LLR-CHO inhibits the trypsin-like activity of the proteasome endopeptidase complex. CAS Number (hemisulfate): 103476-89-7.Formula:C20H38N6O4·H2SO4Purity:97.8380%Color and Shape:WhiteMolecular weight:951.2Leupeptin
CAS:Leupeptin is a protease inhibitor that inhibits the activity of proteases in cells. It has been shown to inhibit transcriptional regulation and apoptosis pathway, as well as possessing anti-inflammatory properties. Leupeptin has been shown to have inhibitory properties against a variety of proteases, including group P2 metalloproteases, cathepsin D, and proteinase 3. This drug has also been shown to prevent neuronal death in experimental models by inhibiting cell lysis. Leupeptin binds to the active site of the enzyme by forming hydrogen bonds with conserved amino acid residues and steric interactions with nearby amino acid residues. The redox potentials of leupeptin are not known, but it is assumed that they are low enough for its antioxidant properties to be effective.Formula:C20H38N6O4H2SOPurity:Min. 90 Area-%Molecular weight:475.6 g/molLeupeptin Hemisulfate
CAS:Leupeptin hemisulfate is a protease inhibitor with cell membrane-permeable, reversible, competitive, and oral activities.Formula:C20H38N6O4H2SO4Purity:90% - ≥98%Color and Shape:White SolidMolecular weight:475.59Leupeptin (Synthetic)
CAS:Please enquire for more information about Leupeptin (Synthetic) including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C20H38N6O4H2SO4Purity:Min. 97 Area-%Molecular weight:475.6 g/molLeupeptin hemisulphate
CAS:Leupeptin hemisulphateFormula:C20H38N6O4·H2SO4Purity:>90%Color and Shape: white to off white powderMolecular weight:951.19g/molLeupeptin hemisulfate
CAS:Formula:C20H38N6O4·5H2SO4Purity:≥ 95%Color and Shape:White to off-white powderMolecular weight:475.59Leupeptin hemisulfate
CAS:Leupeptin is a protein inhibitor that binds to the ubiquitin ligases and inhibits their activity. It has been shown to inhibit the transcriptional regulation of gene expression, which is important in cancer, chronic oral administration, and experimental models. Leupeptin also blocks the binding of proteins to DNA in cell culture and animal models. This leads to decreased production of fatty acids, which are needed for cellular growth and function. Leupeptin also has an anti-depressant effect by blocking the transcriptional regulation of gene expression for serotonin receptors.Formula:C20H38N6O4•(H2SO4)0Purity:Min. 90.0 Area-%Color and Shape:White PowderMolecular weight:475.59 g/mol