CAS: 103816-16-6

11-Desethyl irinotecan is a research tool used in pharmacology and cell biology. It has been shown to inhibit the activity of ion channels, such as potassium channels, by binding to the ligand binding site. 11-Desethyl irinotecan can also be used to determine the role that ion channels play in various physiological processes.

Applications 11-Desethyl Irinotecan is an impurity of the DNA topoisomerase inhibitor Irinotecan (I767500). References Yu,P., et al.: Biol. Pharma. Bull., 35, 1295 (2012); Wang, Y.Q., et al.: Bioorg. Med. Chem., 13, 5592 (2005);