CAS 10391-09-0: Nodosin (terpene)

Nodosin is a bioactive compound classified as a sesquiterpenoid lactone, which is derived from various plant sources of the Artemisia genus. Its mode of action involves modulation of inflammatory pathways and inhibition of key signaling mechanisms, including NF-κB and MAPK, leading to its potential efficacy in managing inflammatory conditions. Nodosin demonstrates a range of biological activities, including anti-inflammatory, anti-cancer, and immunomodulatory effects, making it a valuable subject of research in pharmacology and biochemistry. Researchers are particularly interested in Nodosin's potential to influence cell proliferation and apoptosis, offering implications for cancer therapy. Additionally, its immunomodulatory properties are of significance for autoimmune disorder research. The sesquiterpenoid structure of Nodosin also implicates it in the modulation of oxidative stress responses. Extensive studies are underway to elucidate its precise mechanisms and to explore the therapeutic potentials in various clinical settings. Analysis of Nodosin may also contribute to the understanding of plant-based secondary metabolites and their applications in modern medicine.

Nodosin curbs inflammation by blocking IL-2 and protects liver transplants by raising HO-1 to lessen reperfusion injury.