![(13aS)-2,11-dihydroxy-3,10-dimethoxy-7-methyl-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinolini…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F388646-13as-211-dihydroxy-310-dimethoxy-7-methyl-581313a-tetrahydro-6h-isoquino-32-a-isoquinolinium-chloride.webp&w=3840&q=75)
CAS 104112-82-5: (13aS)-2,11-dihydroxy-3,10-dimethoxy-7-methyl-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinolinium chloride
Formula:C20H24ClNO4
InChI:InChI=1/C20H23NO4.ClH/c1-21-5-4-12-8-19(24-2)18(23)10-15(12)16(21)6-13-7-17(22)20(25-3)9-14(13)11-21;/h7-10,16H,4-6,11H2,1-3H3,(H-,22,23);1H/t16-,21?;/m0./s1
SMILES:C[N+]12CCc3cc(c(cc3[C@@H]2Cc2cc(c(cc2C1)OC)O)[O-])OC.Cl
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Found 9 products.
Phellodendrine chloride
CAS:Natural alkaloidFormula:C20H24NO4ClPurity:≥ 98.0 % (HPLC)Color and Shape:PowderMolecular weight:377.87Phellodendrine Chloride
CAS:Controlled ProductFormula:C20H24ClNO4Color and Shape:NeatMolecular weight:377.87PHELLODENDRINE CHLORIDE
CAS:Formula:C20H24ClNO4Purity:98%Color and Shape:SolidMolecular weight:377.8619Phellodendrine chloride
CAS:Phellodendrine chloride has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli.Formula:C20H24NO4Purity:95%~99%Molecular weight:342.414Phellodendrine chloride
CAS:Phellodendrine chloride combats kidney inflammation by blocking macrophage and T cell activity in glomeruli.Formula:C20H24ClNO4Purity:98.85% - 99.05%Color and Shape:SolidMolecular weight:377.86Phellodendrine chloride
CAS:Phellodendrine chloride is a plant-based alkaloid that has been used historically in the treatment of cancer. Phellodendrine chloride inhibits mitochondrial membrane potential, which can lead to cell death. Jatrorrhizine hydrochloride is a major metabolite of phellodendrine chloride that has been shown to reduce pancreatic tumor size and prolong survival time in mice with pancreatic tumors. This metabolite also blocks the production of reactive oxygen species by inhibiting cytochrome P450 activity. This process leads to a reduction in mitochondrial membrane potential, causing cell death. The extract can be purified from the plant using a liquid chromatography technique prior to use. Phellodendrine chloride is an active ingredient in Panc-1 cells, which are cultured human pancreatic cancer cells. It is effective against these cells at concentrations up to 10 μM. In addition, phellodendrine chloride inhibits the growth of cancerous cells without any toxic effects onFormula:C20H24ClNO4Purity:Min. 95%Molecular weight:377.86 g/mol
