
CAS 104746-03-4: R-10-MONOHYDROXY-DIHYDRO-CARBAMAZEPIN
Formula:C15H14N2O2
InChI:InChI=1/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19)/t14-/m1/s1
SMILES:c1ccc2c(c1)C[C@H](c1ccccc1N2C(=N)O)O
Synonyms:- (10R)-10,11-Dihydro-10-Hydroxy Carbamazepine
- R-(-)-10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide,R-MHD,CGP13698
- (10R)-10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide
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Found 6 products.
(R)-10-Monohydroxy-10,11-dihydro Carbamazepine
CAS:Controlled ProductApplications (R)-10-Monohydroxy-10,11-dihydro Carbamazepine is the metabolite of Oxcarbazepine (OXC) and Eslicarbazepine acetate, (BIA 2-093, ESL), novel central nervous system drugs. ee=98% [α]d=-193 (C=1, pyridine) References Duncan, J., et al.: Br. J. Clin. Pharmacol., 53, 123 (2002), Almeida, L., et al.: J. Clin. Pharmacol., 45, 1062 (2005), Coppola, G., et al.: CNS Drugs, 18, 133 (2004),Formula:C15H14N2O2Color and Shape:NeatMolecular weight:254.28(R)-10-Monohydroxy-10,11-dihydro carbamazepine
CAS:(R)-10-Monohydroxy-10,11-dihydro carbamazepine is a drug that has been shown to be active in vitro against human liver microsomes. It is a metabolite of carbamazepine, which is used for the treatment of neurologic disorders. (R)-10-Monohydroxy-10,11-dihydro carbamazepine has pharmacokinetic properties and plasma concentration-time curves similar to those of its parent compound. It also binds to hepatic CYP2C19 and CYP3A4 enzymes with high affinity, which leads to the inhibition of their activity. The drug has been shown to have a half life of 27 hours in CD1 mice, but it is not known how long it stays in humans.Formula:C15H14N2O2Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:254.28 g/mol(R)-Licarbazepine
CAS:Formula:C15H14N2O2Color and Shape:White To Off-White SolidMolecular weight:254.29(R)-10-Monohydroxy-10,11-dihydro Carbamazepine-d3
CAS:Controlled ProductApplications (R)-10-Monohydroxy-10,11-dihydro Carbamazepine-d3 is labelled (R)-10-Monohydroxy-10,11-dihydro Carbamazepine which is the metabolite of Oxcarbazepine (OXC) and Eslicarbazepine acetate, (BIA 2-093, ESL), novel central nervous system drugs. References Duncan, J., et al.: Br. J. Clin. Pharmacol., 53, 123 (2002), Almeida, L., et al.: J. Clin. Pharmacol., 45, 1062 (2005), Coppola, G., et al.: CNS Drugs, 18, 133 (2004),Formula:C15H11D3N2O2Color and Shape:White To Off-WhiteMolecular weight:257.3