17alpha-Hydroxypregnenolone-21,21,21-D3, with the CAS number 105078-92-0, is a synthetic steroid hormone that is a derivative of pregnenolone. It is characterized by the presence of a hydroxyl group at the 17-alpha position, which is crucial for its biological activity. This compound is typically used in research settings, particularly in studies related to steroidogenesis and the biosynthesis of adrenal hormones. It may also serve as a precursor in the synthesis of other steroid compounds. The presence of deuterium (D3) indicates that it has been isotopically labeled, which can be useful in tracing metabolic pathways or in pharmacokinetic studies. As a steroid, it exhibits lipophilic properties, allowing it to easily cross cell membranes and interact with steroid receptors. Its biological effects are primarily mediated through the modulation of gene expression, influencing various physiological processes such as metabolism, immune response, and development. Safety and handling precautions are essential when working with this compound, as with all steroid hormones.

17ALPHA-HYDROXYPREGNENOLONE-21,21,21-D3

105078-92-0: 17a-Hydroxypregnenolone-21,21,21-d3, 17a-Hydroxypregnenolone-d3, 5-Pregnen-3b,17a-diol-20-one, 5-Pregnen-3,17a-diol-20-one

Applications A labelled metabolite of Pregnenolone (P712200).
References Kramer, R., et al.: J. Steroid Biochemi., 18, 715 (1983), Hiwatashi, A., et al.: J. Biochem., 98, 619 (1985), Eiichi, T., et al.: J. Pharmacol. Sci., 95, 140 (2004),


CAS 105078-92-0: 17ALPHA-HYDROXYPREGNENOLONE-21,21,21-D3

17Alpha-Hydroxy Pregnenolone-d3

Ref: TR-H952322

17α-Hydroxypregnenolone-21,21,21-d3

Ref: 3U-D5329