CAS 105351-70-0: 10H-Furo[3,2-b]naphtho[2,1-d]pyran-10-one,1,6-dimethyl-

Tanshinlactone is a diterpene quinone compound, which is derived from the root of the plant Salvia miltiorrhiza, commonly known as Danshen. This compound is part of a class of natural products that possess notable bioactivities. Tanshinlactone exhibits its mode of action primarily through the induction of apoptosis in cancer cells. It destabilizes mitochondrial membranes, leading to the release of cytochrome c and activation of caspases, which signals the apoptotic pathway. The primary applications of Tanshinlactone are in the research of anticancer therapies. It has shown potential in inhibiting the proliferation of various cancer cells, including breast and liver cancer cell lines. Researchers are exploring its role in multimodal cancer treatment regimens, considering its ability to act synergistically with other chemotherapeutic agents. Further studies are ongoing to elucidate its full mechanism of action and potential clinical applications. Understanding its pharmacokinetics and optimizing its bioavailability continue to be areas of active investigation. Tanshinlactone represents a promising candidate for the development of novel oncological therapeutics.

Tanshinlactone is a natural product of Salvia, Lamiaceae.