CAS 10557-17-2: 1,2-Propanedione, 1-(3-chlorophenyl)-

1-(3-Chlorophenyl)-1,2-propanedione

Impurity Bupropion USP Related Compound E Applications 1-(3-Chlorophenyl)-1,2-propanedione is a metabolite of Bupropion (B689625). Bupropion USP Related Compound E.

1-(3-Chlorophenyl)-1,2-propanedione is a chiral compound that can be used as an intermediate in the synthesis of bupropion. The purity of 1-(3-Chlorophenyl)-1,2-propanedione is determined by measuring the absorbance at a wavelength of 290 nm. The purity is also validated via gas chromatography with a chiral column and monitored using spectroscopy. It should be noted that the compound has been shown to have pharmacopoeia activity and can be measured at a concentration of 0.02 mg/L in acetonitrile.