CAS 1073-13-8: 4,4-Dimethyl-2-Cyclohexen-1-One

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4,4-Dimethyl-2-cyclohexen-1-one is a hydroxy ketone that can be synthesized by the stepwise process. It reacts with chlorine to produce 4,4'-dichlorodimethylcyclohexene. The chloride anion from the chlorination reaction is added to dimethylformamide (DMF) in a borohydride reduction reaction to form 4,4'-dichlorodimethylcyclohexane. The amination reaction of this compound with ammonia produces the desired product 4,4'-dimethyldihydrobenzophenone. The reactions are shown as follows: The total isolated yield for this synthesis is 55%. This synthetic route has an activation energy of 107 kJ/mol and a reaction scheme as shown below:

4,4-Dimethylcyclohex-2-en-1-one