8-Quinolinyl triflate, with the CAS number 108530-08-1, is an organic compound characterized by the presence of a quinoline moiety and a triflate group. It typically appears as a pale yellow to light brown solid and is known for its high reactivity, particularly in nucleophilic substitution reactions. The triflate group (–OSO2CF3) is a potent leaving group, making this compound useful in various synthetic applications, including the formation of carbon-carbon and carbon-heteroatom bonds. Its structure allows for potential applications in medicinal chemistry, particularly in the development of pharmaceuticals, due to the biological activity associated with quinoline derivatives. Additionally, 8-quinolinyl triflate can serve as a versatile electrophile in organic synthesis, facilitating the introduction of functional groups into target molecules. Handling this compound requires caution, as it may be sensitive to moisture and can release toxic gases upon decomposition. Overall, 8-quinolinyl triflate is a valuable reagent in the field of organic chemistry, particularly for researchers focused on synthetic methodologies.

8-QUINOLINYL TRIFLATE

108530-08-1: 8-Quinolinyl Trifluoromethanesulfonate

Quinolin-8-yl trifluoromethanesulfonate

8-Quinolinyl trifluoromethanesulfonate is a drug that has been shown to inhibit the growth of epidermoid carcinoma cells. It is an analog of quinolones. 8-Quinolinyl trifluoromethanesulfonate binds to the drug target site on tubulin, which is required for cell division, and prevents polymerization into microtubules. The compound also inhibits the release of cytochrome c from mitochondria, leading to decreased mitochondrial membrane potential and apoptosis. This drug has been shown to have no effect on normal human skin fibroblasts or human erythrocytes in vitro.

CAS 108530-08-1: 8-QUINOLINYL TRIFLATE

Quinolin-8-yl trifluoromethanesulfonate

Ref: 10-F732399

8-Quinolinyl Trifluoromethanesulfonate

Ref: 3D-FQ84340