
CAS 108736-10-3: Ramiprilat Diketopiperazine
Formula:C21H21D5N2O4
InChI:InChI=1/C21H26N2O4/c1-13-19(24)23-16-9-5-8-15(16)12-18(23)20(25)22(13)17(21(26)27)11-10-14-6-3-2-4-7-14/h2-4,6-7,13,15-18H,5,8-12H2,1H3,(H,26,27)/t13-,15-,16-,17+,18-/m0/s1/i2D,3D,4D,6D,7D
Synonyms:- [3S-[2(R*),3a,5ab,8ab,9ab]]-Decahydro-3-methyl-1,4-dioxo-a-(2-phenylethyl)-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic Acid
- [3S-[2(R*),3a,5a,8a,9a]]-Decahydro-3-methyl-1,4-dioxo-a-(2-phenylethyl)-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic Acid
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Ramiprilat diketopiperazine
CAS:Ramiprilat diketopiperazine is a drug that is metabolized by glucuronidation. It is an analog of ramipril, which is a member of the angiotensin-converting enzyme (ACE) inhibitors. Ramiprilat diketopiperazine has been shown to be clinically effective in reducing blood pressure and improving left ventricular function in patients with chronic heart failure. The reanalysis and validation of the bioanalytical method for analysis of ramiprilat diketopiperazine have been completed, and the method was validated for use in clinical studies. The analytes were measured using chromatography with ultraviolet detection or with liquid chromatography-mass spectrometry-mass spectrometry. The method development for the analysis of glucuronide metabolites has also been completed, and these metabolites were quantified using high performance liquid chromatography with UV detection or with gas chromatography-mass spectrometry-mass spectrometry.Formula:C21H26N2O4Purity:Min. 95%Molecular weight:370.44 g/molRamiprilat Diketopiperazine-d5
CAS:Controlled ProductApplications A labelled metabolite of Ramipril (R111000). References Tabata, S., et al.: J. Biopharm. Sci., 1, 235 (1990),Formula:C21D5H21N2O4Color and Shape:NeatMolecular weight:375.473Ramipril EP Impurity K (Ramiprilat Diketopiperazine)
CAS:Formula:C21H26N2O4Color and Shape:White To Off-White SolidMolecular weight:370.45Ramiprilat Diketopiperazine(Mixture of Diastereoisomers)
CAS:Controlled ProductImpurity Ramipril EP Impurity K Applications Ramiprilat Diketopiperazine (Mixture of Diastereoisomers) (Ramipril EP Impurity K) is a metabolite of Ramipril (R111000). References Tabata, S., et al.: J. Biopharm. Sci., 1, 235 (1990),Formula:C21H26N2O4Color and Shape:White To Off-WhiteMolecular weight:370.44