CAS 109-05-7: 2-Methylpiperidine

2-Methylpiperidine is a molecule that can be synthesized by solid-phase synthesis. It is an inhibitor of nicotinic acetylcholine receptors and has been shown to have a blood pressure-lowering effect. 2-Methylpiperidine has been found to inhibit the reaction between nicotinic acetylcholine and the nicotinic acetylcholine receptor, which inhibits the response of the muscle cell. The inhibitory effect of 2-methylpiperidine on this reaction is due to its hydroxyl group, which forms hydrogen bonds with the lysine amino acid in the receptor. This inhibition prevents the passage of ions through the membrane and leads to decreased muscle contractions.

2-Methylpiperidine, is used for the oxidation of secondary amines to nitrones by means of H2O2 catalyzed by Sodium tungsten oxide dihydrate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

2-Methylpiperidine