CAS 109-06-8: 2-Methylpyridine

2-Methylpyridine is a compound that has been investigated for its potential use as an anticancer drug. It has been shown to inhibit hyperproliferation of carcinoma cell lines, and it also displays antimetastatic effects. 2-Methylpyridine binds to the toll-like receptor pathway and inhibits the production of proinflammatory cytokines such as picolinic acid. 2-Methylpyridine is also able to inhibit x-ray crystal structures, which may be due to its ability to interact with hydrogen fluoride. The reaction mechanism of 2-methylpyridine is still not well understood, but it is thought to involve picolinic acid and the hydrophobic effect.

Applications 2-Picoline is used as a reagent in the synthesis of 2-Picolineborane, a non-toxic alternative to sodium borohydride for the labelling of oligosaccharides. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Renee Ruhaak, L., et al.: Proteomics, 10, 2330 (2010)

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

2-Picoline is used as an intermediate in agrochemicals and pharmaceuticals. It serves as a solvent as well as to prepare dyes and resins. It finds application as a constituent in cigarette smoke, bone oil, coal tar and coke oven emissions. Further, it acts as a precursor of 2-vinylpyridine, picolinic acid and nitrapyrin. It is also employed to study the electron and proton transfer reactions of lumiflavin. In addition, it is used in the synthetic pathway for the preparation of dearomatized, allylated and carbon-hydrogen bond activated pyridine derivatives. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.