CAS 109632-08-8: 1-(Ethylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol

Amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters, salts therof, nesoi

Impurity Metoprolol EP Impurity A Applications C-Desmethyl Metoprolol (Metoprolol EP Impurity A) is a new byproduct detected in Metoprolol tartrate. Metoprolol impurity. References Erickson, M., et al.: J. Pharma. Biomed. Analysis, 13, 567 (1995), Phinney, K., et al.: Chirality, 15, 287 (2003), Zheng, J., et al.: Anal. Chem., 78, 1535 (2006),

C-Desmethyl metoprolol is a metabolite of metoprolol, which is a beta blocker. It has been shown to have an increased reaction rate and ionization detector response in comparison to its parent compound. The nature of the product is non-polar, so it can be used in silicone or supercritical fluid chromatography. The kinetic of the product has been observed to be slower than that of metoprolol. This product also has a tailing effect, which may result from the presence of methylphenyl groups on the molecule.