CAS 109889-09-0: Granisetron
Formula:C18H24N4O
InChI:InChI=1/C18H24N4O/c1-21-13-6-5-7-14(21)11-12(10-13)19-18(23)17-15-8-3-4-9-16(15)22(2)20-17/h3-4,8-9,12-14H,5-7,10-11H2,1-2H3,(H,19,23)/t12-,13+,14-
InChI key:InChIKey=MFWNKCLOYSRHCJ-BTTYYORXNA-N
SMILES:C(N[C@H]1C[C@@]2(N(C)[C@](C1)(CCC2)[H])[H])(=O)C=3C=4C(N(C)N3)=CC=CC4
Synonyms:- 1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide
- 1H-Indazole-3-carboxamide, 1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-, endo-
- 1H-Indazole-3-carboxamide, 1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-
- 9-Azabicyclo[3.3.1]nonane, 1H-indazole-3-carboxamide deriv.
- Apf 530
- Brl 43694
- Brl 43964
- Granisetron free base
- Kevatril
- Sancuso
- Sustol
- See more synonyms
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Found 7 products.
Granisetron Hydrochloride
CAS:Formula:C18H24N4O·HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:348.88Granisetron
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFormula:C18H24N4OColor and Shape:Off-White Light Yellow PowderMolecular weight:312.195011-Methyl-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-indazole-3-carboxamide
CAS:Controlled Product1-Methyl-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-indazole-3-carboxamide is a chemical inhibitor of the 5HT2 receptor, which is responsible for regulating nausea and vomiting. It has been shown to have antiemetic properties, and can be used in chemotherapy to control nausea and vomiting. The 5HT2 receptor is coupled to Gs proteins and inhibits adenylyl cyclase activity, while 1MMAI binds to the 5HT2A receptor and blocks serotonin from binding. This prevents serotonin from activating Gq protein receptors, which are involved in the generation of intracellular calcium concentrations that lead to neurotransmitter release. 1MMAI also inhibits the activation of phospholipase C by serotonin, resulting in decreased levels of diacylglycerol (DAG) and inositol triphosphate (IP3). These changes inhibit plateFormula:C18H24N4OPurity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:312.41 g/molGranisetron
CAS:Granisetron, a serotonin receptor (5HT-3 selective) antagonist, is used as an antinauseant and antiemetic for cancer chemotherapy.Formula:C18H24N4OColor and Shape:SolidMolecular weight:312.41Granisetron
CAS:Controlled ProductApplications Granisetron is a selective 5HT-3 antagonist.Formula:C18H24N4OColor and Shape:NeatMolecular weight:312.41
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