3-Formyl-4-methylphenylboronic acid is an organic compound characterized by the presence of a boronic acid functional group, which is known for its ability to form reversible covalent bonds with diols. This compound features a phenyl ring substituted with both a formyl group and a methyl group, contributing to its reactivity and potential applications in organic synthesis and medicinal chemistry. The formyl group (–CHO) provides an aldehyde functionality, making it useful in various chemical reactions, including condensation and coupling reactions. The boronic acid moiety allows for participation in Suzuki coupling reactions, which are vital in the formation of carbon-carbon bonds. This compound is typically a solid at room temperature and may exhibit solubility in polar solvents. Its unique structure and functional groups make it a valuable intermediate in the synthesis of pharmaceuticals and agrochemicals. Additionally, the presence of both electron-withdrawing and electron-donating groups influences its reactivity and interaction with other chemical species.

3-Formyl-4-methylphenylboronic acid

1106869-99-1: (3-Formyl-4-methyl-phenyl)boronic acid

3-Formyl-4-methylphenylboronic acid is a white crystalline compound that is soluble in organic solvents. It is used as a reagent for the synthesis of ketones, esters, and amides. 3-Formyl-4-methylphenylboronic acid can be prepared by the reaction of boron trifluoride with ethylene glycol in the presence of p-toluenesulfonic acid at room temperature. This product can be purified by recrystallization from ether or tetrahydrofuran and then converted to acetal derivatives such as methyl 3-(3-formyl-4-methylphenyl)propanoate. The large scale production of this compound requires magnesium, ethylene glycol, and p-toluenesulfonic acid.

CAS 1106869-99-1: 3-Formyl-4-methylphenylboronic acid

3-Formyl-4-methylphenylboronic acid

Ref: IN-DA00HBR9

3-Formyl-4-methylphenylboronic acid

Ref: 54-OR360196

3-Formyl-4-methylphenylboronic acid

Ref: 3D-GUB86999

(3-Formyl-4-methylphenyl)boronic acid

Ref: 10-F219055