CAS 111409-79-1: Silane, (bromoethynyl)tris(1-methylethyl)-

(Bromoethynyl)triisopropylsilane

(2-Bromoethynyl)tris(propan-2-yl)silane is a synthetically useful compound that has been used in the synthesis of amines, as well as in the preparation of triazoles. It can be used to produce chaperones and antitumoural drugs, such as solvents and palladium-catalyzed cross-coupling reactions. This compound is an efficient source of ethynyl groups for cross-coupling reactions with a wide range of amine partners. The ring-opening reaction of this compound with pyrroles provides two equivalents of propargyl alcohols, which can then be converted into an array of products including amino acids and pharmaceuticals.