CAS 1134-23-2: cycloate

Cycloate, a herbicide, blocks synthesis of plant-wax fatty acids and resorcinolic lipid precursors.

Applications Cycloate-D5 is a labelled analogue of Cycloate (C989320). Cycloate is a thiocarbamate herbicide that is used to maintain crop protection from weeds. Unlike other herbicides, cycloate is classified as not likely to be a carcinogen to humans by the United States Environmental Protection Agency. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Schweizer, E.: Weed Res., 14, 39 (1974); US-EPA; Chapter IV. Risk Management, Reregistration and Tolerance Reassessment Decision. Reregistration Eligibility Decision (RED) for Cycloate (S-ethyl cyclohexyl(ethyl)thiocarbamate). 738-R-04-014; EPA: Washington, D.C., 2004, 33.

Cycloate is an antimicrobial agent that inhibits the biosynthesis of fatty acids in bacteria. Cycloate binds to the enzyme fatty acid synthase, which catalyzes the conversion of malonic acid and acetyl-coenzyme A to form acetic acid and malonyl-coenzyme A. Cycloate also binds to a number of other enzymes including those involved in the synthesis of p-hydroxybenzoic acid and herbicides. Cycloate has been shown to inhibit the growth of bacterial strains including Escherichia coli, Bacillus subtilis, and Salmonella typhimurium. It can be used as a herbicide for weed control on lawns or as an additive for crop production.