CAS 113893-08-6: Benzothiophene-3-boronic acid

Benzo[b]thiophene-3-boronic acid

Applications Benzo[b]thien-3-ylboronic acid is used in the synthesis and evaluation of dual wavelength fluorescent benzo[b]thiophene boronic acid derivatives for sugar/glycoprotein sensing. References Akay, S., et al.: Chem. Biol. Drug Des., 70, 279 (2007)

Benzo[b]thiophene-3-boronic acid is a boronic acid that can be used in the synthesis of estranes. It is a key intermediate for organic chemists, who use it as a building block for synthesis of organic molecules. This compound can be obtained through electrochemical oxidation of benzo[b]thiophene-3-carboxylic acid with a palladium electrode and an electrolyte solution. The reaction is performed in an evaporator, which removes the solvent and leaves a solid residue. The final product can be purified by recrystallization or distillation. Benzo[b]thiophene-3-boronic acid reacts with electron-rich aromatic compounds to form cross-coupling products, which are often used as ligands in metal complexes.