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CAS 1146699-66-2: Pentanamide,2-[[(4-chlorophenyl)sulfonyl][[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoro-,(2R)-
Formula:C20H17ClF4N4O4S
Synonyms:- (2R)-2-[N-[(4-Chlorophenyl)sulfonyl]-N-[[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoropentanamide
- (2R)-2-[(4-chlorophenyl)sulfonyl-[[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoro-pentanamide
- Avagacestat
- Bms-708163
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Avagacestat
CAS:Avagacestat (BMS-708163) (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM,Formula:C20H17ClF4N4O4SPurity:98.87% - 99.77%Color and Shape:SolidMolecular weight:520.89Ref: TM-T6249
1mg63.00€5mg120.00€10mg197.00€25mg376.00€50mg547.00€100mg793.00€200mg1,064.00€1mL*10mM (DMSO)139.00€Pentanamide, 2-[[(4-chlorophenyl)sulfonyl][[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoro-, (2R)-
CAS:Formula:C20H17ClF4N4O4SPurity:99%Color and Shape:SolidMolecular weight:520.885(R)-2-[[4-chlorophenyl)sulfonyl][[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoropentanamide
CAS:Controlled ProductApplications Avagacestat acts as a γ-secretase inhibitor allowing for treatment of ALzheimer’s disease. On addition it has seen uses targeting embryonic signaling pathways, which control stem cell and cellular development process in cancer therapy. References Harris, PJ. et al.: Expert. Opin. Ther. Tar., 16, 131 (2012); Gilman, K.W. et al.: ACS Med. Chem. Lett., 1, 120 (2010);Formula:C20H17ClF4N4O4SColor and Shape:NeatMolecular weight:520.88(R)-2-((4-Chloro-N-(2-Fluoro-4-(1,2,4-Oxadiazol-3-Yl)Benzyl)Phenyl)Sulfonamido)-5,5,5-Trifluoropentanamide
CAS:(R)-2-((4-Chloro-N-(2-Fluoro-4-(1,2,4-Oxadiazol-3-Yl)Benzyl)Phenyl)Sulfonamido)-5,5,5-TrifluoropentanamideMolecular weight:520.89g/molBMS 708163
CAS:Inhibitor of γ-secretase; Alzheimer's disease treatmentFormula:C20H17ClF4N4O4SPurity:Min. 95%Molecular weight:520.89 g/mol
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