CAS 115344-47-3: Siguazodan
Formula:C14H16N6O
InChI:InChI=1S/C14H16N6O/c1-9-7-12(21)19-20-13(9)10-3-5-11(6-4-10)18-14(16-2)17-8-15/h3-6,9H,7H2,1-2H3,(H,19,21)(H2,16,17,18)
InChI key:InChIKey=NUHPODZZKHQQET-UHFFFAOYSA-N
SMILES:CC1C(C2=CC=C(N=C(NC#N)NC)C=C2)=NNC(=O)C1
Synonyms:- 1-Cyano-2-Methyl-3-[4-(4-Methyl-6-Oxo-1,4,5,6-Tetrahydropyridazin-3-Yl)Phenyl]Guanidine
- Guanidine, N-cyano-N′-methyl-N′′-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-
- N-Cyano-N'-Methyl-N'-[4-(1,4,5,6-Tetrahydro-4-Methyl-6-Oxo-3-Pyridazinyl)Phenyl]Guanidine
- N-Cyano-Nmethyl-N��-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]guanidine
- Siguazodan (SKF 94836)
- Siguazodan, N-Cyano-Nμ-methyl-N-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]guanidine
- Sk And F-94836
- Skf 94836
- Siguazodan
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Found 4 products.
Siguazodan
CAS:Siguazodan is a phosphodiesterase inhibitor that is used for the treatment of congestive heart failure and bowel disease. Siguazodan inhibits the activity of cyclic nucleotide phosphodiesterases, which are enzymes that regulate the concentration of cyclic AMP (cAMP) in cells. It has anti-inflammatory properties and can be used to inhibit the bronchoconstrictor response. Siguazodan also inhibits phosphodiesterase-4 (PDE4), an enzyme that degrades cAMP, increasing intracellular concentrations and causing bronchodilation.Formula:C14H16N6OPurity:Min. 95%Molecular weight:284.32 g/molGuanidine, N-cyano-N'-methyl-N''-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-
CAS:Formula:C14H16N6OPurity:99.0%Color and Shape:SolidMolecular weight:284.3164Siguazodan
CAS:Siguazodan (SKF 94836) is an effective, selective, orally active phosphodiesterase III ((PDE-III)) inhibitor with an IC50 of 117 nM.Formula:C14H16N6OPurity:99.63% - 99.77%Color and Shape:SolidMolecular weight:284.32Ref: TM-T12913
1mg42.00€5mg88.00€10mg127.00€25mg264.00€50mg424.00€100mg655.00€200mg924.00€1mL*10mM (DMSO)87.00€
![Guanidine, N-cyano-N'-methyl-N''-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA000GMB.jpg&w=3840&q=75)
