A-conotoxin SI is a peptide derived from the venom of the Conus snail, specifically the species Conus striatus. This compound is classified as a conotoxin, which are small, disulfide-rich peptides that target various ion channels and receptors in the nervous system. A-conotoxin SI is known for its selective inhibition of nicotinic acetylcholine receptors, particularly those containing the α3 and β2 subunits, making it a valuable tool for studying synaptic transmission and potential therapeutic applications in pain management and neurological disorders. The structure of A-conotoxin SI features multiple disulfide bonds that contribute to its stability and biological activity. Its specificity and potency make it a subject of interest in pharmacological research, particularly in the development of novel analgesics. Additionally, due to its origin from marine organisms, A-conotoxin SI exemplifies the potential of natural products in drug discovery and the exploration of new therapeutic avenues.

A-conotoxin si

115797-06-3: a-Conotoxin SI, Conus striatus,  Alpha-Conotoxin Si,  1-[(2S)-4-amino-2-[[(2R)-2-[[(2R)-2-[[(2S,3S)-2-amino-3-methyl-pentanoyl]amino]-3-sulfanyl-propanoyl]amino]-3-sulfanyl-propanoyl]amino]-4-oxo-butanoyl]-N-[(1S)-2-[[(1R)-2-[[2-[(2S)-2-[[(1S)-5-amino-1-[[(1S)-2-[[(1S)-2-[[(1R)-2-amino-2-oxo-1-(sulfanylmethyl)ethyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-1-[(4-hydroxyphenyl)methyl]-2-oxo-ethyl]carbamoyl]pentyl]carbamoyl]pyrrolidin-1-yl]-2-oxo-ethyl]amino]-2-oxo-1-(sulfanylmethyl)ethyl]amino]-1-methyl-2-oxo-ethyl]pyrrolidine-2-carboxamide

Sourced from the marine snail, conus striatus, this synthetic cone snail toxin is a nicotinic acetylcholine receptor blocker. This product has disulfide bonds between Cys2-Cys7 and Cys3-Cys7.

CAS 115797-06-3: A-conotoxin si

α-Conotoxin SI

Ref: 3D-PCN-4228-V