10-Hydroxyamitriptyline is a chemical compound that is a derivative of amitriptyline, which is primarily known as an antidepressant. This substance is characterized by the presence of a hydroxyl group at the 10-position of the dibenzocycloheptene structure, which contributes to its pharmacological properties. It is classified as a tricyclic antidepressant (TCA) and exhibits a range of biological activities, including potential effects on neurotransmitter reuptake, particularly serotonin and norepinephrine. The compound is typically found in a crystalline form and is soluble in organic solvents. Its molecular structure includes multiple aromatic rings, which are common in many pharmaceuticals, enhancing its interaction with biological targets. While 10-hydroxyamitriptyline itself may not be widely used in clinical settings, it serves as an important metabolite of amitriptyline, contributing to the overall pharmacokinetics and therapeutic effects of the parent drug. Research into its specific effects and potential applications continues to evolve within the field of medicinal chemistry.

10-hydroxyamitriptyline

1159-82-6: 5H-Dibenzo(a,d)cyclohepten-10-ol, 5-(3-(dimethylamino)propylidene)-10,11-dihydro-, (5Z)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d][7]annulen-10-ol, 10-Hydroxyamitriptyline

CAS 1159-82-6: 10-hydroxyamitriptyline

(5EZ,10RS)-5-[3-(Dimethyl-amino)propylidene]-10,11-dihydro-5H-dibenzo[a,d][7]annulen-10-ol

Ref: 86-MM0062.05

(5EZ,10RS)-5-[3-(Dimethyl-amino)propylidene]-10,11-dihydro-5H-dibenzo[a,d][7]annulen-10-ol

Ref: TR-MM0062.05

(5EZ,10RS)-5-[3-(Dimethyl-amino)propylidene]-10,11-dihydro-5H-dibenzo[a,d][7]annulen-10-ol

Ref: TR-MM0062.05-0025-4AMP

Amitriptyline EP Impurity F (10-Hydroxy Amitriptyline)

Ref: 4Z-A-209

Amitriptyline EP Impurity F-d6

Ref: 4Z-A-2015