CAS 115956-12-2: Dolasetron
Formula:C19H20N2O3
InChI:InChI=1/C19H20N2O3/c22-18-10-21-12-5-11(18)6-13(21)8-14(7-12)24-19(23)16-9-20-17-4-2-1-3-15(16)17/h1-4,9,11-14,20H,5-8,10H2/t11?,12-,13+,14+
InChI key:InChIKey=UKTAZPQNNNJVKR-MMUVGSQPNA-N
SMILES:O(C(=O)C=1C=2C(NC1)=CC=CC2)[C@@H]3C[C@]4([N@]5[C@](CC(C4)C(=O)C5)(C3)[H])[H]
Synonyms:- (2alpha,6alpha,8alpha,9abeta)-Octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl-1H-indole-3-carboxylate
- (6R)-3-oxooctahydro-2H-2,6-methanoquinolizin-8-yl 1H-indole-3-carboxylate
- 1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, (2α,6α,8α,9aβ)-
- 1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, stereoisomer
- 1H-indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester
- 2,6-Methano-2H-quinolizine, 1H-indole-3-carboxylic acid deriv.
- 3-oxooctahydro-2H-2,6-methanoquinolizin-8-yl 1H-indole-3-carboxylate
- 3-oxooctahydro-2H-2,6-methanoquinolizin-8-yl 1H-isoindole-3-carboxylate
- Anemet
- Mdl 73147
- Dolasetron
- See more synonyms
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Found 10 products.
1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, stereoisomer
CAS:Formula:C19H20N2O3Purity:98%Color and Shape:SolidMolecular weight:324.3737Dolasetron
CAS:Formula:C19H20N2O3Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalineMolecular weight:324.38Dolasetron-d4 (Indole-d4)
CAS:Formula:C19H16D4N2O3Color and Shape:Off-White SolidMolecular weight:328.40Octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester
CAS:Dolasetron mesylate is a mesylate of the biologically active form of dolasetron, which is an octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester. Dolasetron has been shown to be effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy or radiation therapy. It has been approved for use in adults with cancer who have not responded to other treatments. Dolasetron is rapidly absorbed from the gastrointestinal tract and is then distributed throughout the body, including into the brain. The elimination half life of dolasetron mesylate is about 2 hours and it binds to plasma proteins. Dolasetron mesylate specifically binds to serotonin receptors, which are found on cells in the gut. This binding inhibits serotonin induced contraction of bowel smooth muscle cells.Formula:C19H20N2O3Purity:Min. 95%Color and Shape:White To Off-White To Grey SolidMolecular weight:324.37 g/molDolasetron
CAS:Dolasetron (MDL-73147)(MDL-73147) is a serotonin 5-HT3 receptor antagonist. Dolasetron is used to treat nausea and vomiting following chemotherapy.Formula:C19H20N2O3Purity:99.84% - 99.86%Color and Shape:White PowderMolecular weight:324.37Dolasetron
CAS:Controlled ProductApplications Bridged pseudopelletierine derivative; specific serotonin (5HT3) receptor antagonist. Antiemetic. References Boeijinga, P.H., et al.: Eur. J. Pharmacol., 219, 9 (1992), Miller, R.C., et al., Drug Dev. Res., 28, 87 (1993), Fauser, A.A., et al.: Eur. J. Cancer, 32, 1523 (1996), Graczyk, S.G., et al.: Anesth. Analg., 84, 325 (1997),Formula:C19H20N2O3Color and Shape:NeatMolecular weight:324.37
