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CAS 115966-68-2: Histatin 5

Formula:C133H195N51O33
InChI:InChI=1/C133H195N51O33/c1-71(164-120(206)96(46-76-54-146-65-158-76)181-128(214)103(62-185)183-110(196)84(138)52-108(193)194)109(195)167-86(18-5-9-35-134)113(199)172-91(24-15-41-154-133(143)144)118(204)178-99(49-79-57-149-68-161-79)125(211)176-95(45-75-53-145-64-157-75)112(198)156-60-105(189)165-93(43-73-25-29-82(187)30-26-73)121(207)173-87(19-6-10-36-135)114(200)171-90(23-14-40-153-132(141)142)115(201)169-88(20-7-11-37-136)116(202)175-94(42-72-16-3-2-4-17-72)122(208)179-97(47-77-55-147-66-159-77)124(210)174-92(33-34-107(191)192)119(205)170-89(21-8-12-38-137)117(203)177-100(50-80-58-150-69-162-80)126(212)180-101(51-81-59-151-70-163-81)127(213)184-104(63-186)129(215)182-98(48-78-56-148-67-160-78)123(209)168-85(22-13-39-152-131(139)140)111(197)155-61-106(190)166-102(130(216)217)44-74-27-31-83(188)32-28-74/h2-4,16-17,25-32,53-59,64-71,84-104,185-188H,5-15,18-24,33-52,60-63,134-138H2,1H3,(H,145,157)(H,146,158)(H,147,159)(H,148,160)(H,149,161)(H,150,162)(H,151,163)(H,155,197)(H,156,198)(H,164,206)(H,165,189)(H,166,190)(H,167,195)(H,168,209)(H,169,201)(H,170,205)(H,171,200)(H,172,199)(H,173,207)(H,174,210)(H,175,202)(H,176,211)(H,177,203)(H,178,204)(H,179,208)(H,180,212)(H,181,214)(H,182,215)(H,183,196)(H,184,213)(H,191,192)(H,193,194)(H,216,217)(H4,139,140,152)(H4,141,142,153)(H4,143,144,154)/t71-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-/m0/s1
SMILES:C[C@@H](C(=N[C@@H](CCCCN)C(=N[C@@H](CCCNC(=N)N)C(=N[C@@H](Cc1cnc[nH]1)C(=N[C@@H](Cc1cnc[nH]1)C(=NCC(=N[C@@H](Cc1ccc(cc1)O)C(=N[C@@H](CCCCN)C(=N[C@@H](CCCNC(=N)N)C(=N[C@@H](CCCCN)C(=N[C@@H](Cc1ccccc1)C(=N[C@@H](Cc1cnc[nH]1)C(=N[C@@H](CCC(=O)O)C(=N[C@@H](CCCCN)C(=N[C@@H](Cc1cnc[nH]1)C(=N[C@@H](Cc1cnc[nH]1)C(=N[C@@H](CO)C(=N[C@@H](Cc1cnc[nH]1)C(=N[C@@H](CCCNC(=N)N)C(=NCC(=N[C@@H](Cc1ccc(cc1)O)C(=O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)N=C([C@H](Cc1cnc[nH]1)N=C([C@H](CO)N=C([C@H](CC(=O)O)N)O)O)O
Synonyms:
  • Histatin-5
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Found 2 products.
  • Histatin 5

    CAS:
    Histatin 5 is a peptide that has been shown to have antimicrobial activity against Candida albicans, Candida glabrata, and Cryptococcus albicans. It is believed to exert its effect by binding to copper ions and inhibiting the mitochondrial functions of the pathogen. Histatin 5 also has pro-apoptotic properties and may be used as an experimental treatment for infectious diseases caused by opportunistic fungal strains.
    Formula:C133H195N51O33
    Purity:Min. 95%
    Molecular weight:3,036.3 g/mol

    Ref: 3D-FH73440

    1mg
    1,017.00€
    500µg
    749.00€
  • Histatin 5

    CAS:
    Histatin 5, a human saliva peptide, blocks MMP-2 and MMP-9 at IC50s of 0.57/0.25 μM and kills fungi.
    Formula:C133H195N51O33
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3036.29

    Ref: TM-TP1741

    1mg
    172.00€
    5mg
    593.00€
    10mg
    940.00€