1H-Benzimidazole-5-carboxamide, with the CAS number 116568-17-3, is a chemical compound characterized by its benzimidazole core structure, which consists of a fused benzene and imidazole ring. This compound features a carboxamide functional group at the 5-position of the benzimidazole ring, contributing to its potential biological activity. It is typically a white to off-white solid and is soluble in polar solvents, which may include water and dimethyl sulfoxide. The presence of the carboxamide group enhances its ability to form hydrogen bonds, influencing its interactions with biological targets. 1H-Benzimidazole-5-carboxamide is of interest in medicinal chemistry due to its potential applications in pharmaceuticals, particularly as an anti-cancer or anti-inflammatory agent. Its structural properties allow for various modifications, which can lead to derivatives with enhanced efficacy or selectivity. As with many benzimidazole derivatives, it may exhibit a range of biological activities, making it a subject of research in drug development and therapeutic applications.

1H-BENZIMIDAZOLE-5-CARBOXAMIDE

116568-17-3: 1H-Benzimidazole-5-carboxamide(9CI)

Benzoimidazole-5-carboxylic acid amide is a molecule that has been shown to inhibit the production of inflammatory cytokines and chemokines, such as tumor necrosis factor-α, interleukin-8, and monocyte chemotactic protein-1. It also inhibits the release of proinflammatory eicosanoids such as prostaglandin E2, leukotriene B4, and thromboxane A2. Benzoimidazole-5-carboxylic acid amide is currently being investigated for potential use in treatment of autoimmune diseases and insulin resistance.

CAS 116568-17-3: 1H-BENZIMIDAZOLE-5-CARBOXAMIDE

1H-Benzoimidazole-5-carboxylic acid amide

Ref: 3D-REA56817

1H-Benzoimidazole-5-carboxylic acid amide

Ref: 10-F038332

1H-Benzimidazole-6-carboxamide

Ref: IN-DA000CS0