CAS: 1172118-03-4

PI3K-gamma inhibitor 1 is a small molecule inhibitor, which is selectively synthesized for targeting the PI3K-gamma isoform. This inhibitor is derived through precise medicinal chemistry, involving the synthesis of compounds that specifically interact with the catalytic domain of the phosphoinositide 3-kinase gamma (PI3K-γ) enzyme. Its mode of action involves the selective inhibition of the PI3K-γ pathway, a critical signaling route responsible for modulating immune cell functions and inflammatory responses. This selectivity towards PI3K-gamma makes it a vital tool for dissecting the roles of this specific isoform in cellular mechanisms. It is primarily used in research settings to explore therapeutic avenues for inflammatory and immune-related disorders, as well as for investigating cancer and cardiovascular diseases where immune modulation plays a vital role. Through this targeted inhibition, researchers can study the downstream effects on cellular processes, offering insights into novel therapeutic strategies and potential drug development pathways.

PI3Kγ inhibitor 1 is a inhibitor of PI3Kδ and PI3Kγ.