CAS: 1176-09-6

Raptinal

Raptinal activates caspase-3 directly and initiates intrinsic caspase-dependent apoptosis pathway in multiple cell lines.

Raptinal is a molecule that induces apoptotic cell death by interacting with hepg2 cells. It has been shown to induce the release of pro-inflammatory cytokines, such as IL-1β and IL-8, from the cells. Raptinal activates the apoptosis pathway by inducing caspase-3, which then cleaves poly(ADP-ribose) polymerase (PARP), leading to DNA fragmentation and cell death. The mechanism of action for Raptinal is similar to imidazotetrazine, an anti-cancer drug that also induces apoptosis in cancer cells. Raptinal has also been shown to inhibit tumor growth in vivo in animal models of meningioma. Raptinal has antioxidant properties and can protect cells from oxidative damage caused by free radicals. This activity may be due to its ability to scavenge reactive oxygen species or inhibit lipid peroxidation pathways.

9H,9'H-[9,9'-Bifluorene]-9,9'-Dicarbaldehyde