5'-Inosinic acid, 2',3'-dideoxy- is a nucleoside analog that plays a significant role in biochemical research, particularly in the study of nucleic acid metabolism and antiviral drug development. This compound is characterized by its structural modification of the natural nucleoside inosine, specifically the absence of a hydroxyl group at the 2' and 3' positions of the ribose sugar, which contributes to its unique properties. The modification enhances its stability and alters its interaction with nucleic acid polymerases, making it a valuable tool in the exploration of RNA and DNA synthesis. Additionally, 5'-Inosinic acid, 2',3'-dideoxy- may exhibit antiviral activity, as many dideoxynucleosides are known to inhibit viral replication by terminating the elongation of viral DNA or RNA chains. Its applications extend to molecular biology and pharmacology, where it is utilized in the development of therapeutic agents targeting various viral infections. Overall, this compound exemplifies the importance of structural modifications in the design of effective nucleoside analogs.

5'-Inosinic acid, 2',3'-dideoxy-

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2',3'-Dideoxyinosine-5'-monophosphate sodium salt (ddI-MP) is an antiviral drug that is effective against HIV. It inhibits the reverse transcriptase enzyme, which is responsible for the conversion of RNA to DNA. ddI-MP has cytotoxic properties and prevents the production of DNA and protein. This agent also has a prophylactic effect against retroviruses, such as HIV, by preventing them from establishing latency in lymphocytes.

CAS 117947-01-0: 5'-Inosinic acid, 2',3'-dideoxy-

2',3'-Dideoxyinosine-5'-monophosphate sodium salt

Ref: 3D-ND28881