CAS 118-10-5: Cinchonine
Formula:C19H22N2O
InChI:InChI=1S/C19H22N2O/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17/h2-7,9,13-14,18-19,22H,1,8,10-12H2/t13-,14-,18+,19-/m0/s1
InChI key:InChIKey=KMPWYEUPVWOPIM-QAMTZSDWSA-N
SMILES:[C@@H](O)([C@@]1([N@@]2C[C@H](C=C)[C@](C1)(CC2)[H])[H])C=3C4=C(N=CC3)C=CC=C4
Synonyms:- (3alpha,9R)-cinchonan-9-ol
- (3alpha,9S)-cinchonan-9-ol
- (4beta,9S)-cinchonan-1-ium-9-ol
- (8R,9S)-Cinchonine
- (8alpha,9S)-cinchonan-9-ol
- (9R)-cinchonan-9-ol
- (9S)-9-hydroxycinchonan-1-ium
- (9S)-cinchonan-9-ol
- Alpha-(5-Vinyl-2-Quinuclidinyl)-4-Quinolinemethanol
- Cinchonan-9-Ol
- Cinchonan-9-ol, (9S)-
- See more synonyms
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Found 13 products.
(+)-Cinchonine
CAS:Purity:98.0%Color and Shape:Solid, Crystalline Powder or PowderMolecular weight:294.39801025390625Cinchonine
CAS:Formula:C19H22N2OPurity:(Titration) ≥ 99.0%Color and Shape:White to almost white crystalline powderMolecular weight:294.39(+)-cinchonine
CAS:Cinchona alkaloidFormula:C19H22N2OPurity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:294.4Cinchonine
CAS:Formula:C19H22N2OPurity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:294.40Cinchonine, 99%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C19H22N2OPurity:99%Color and Shape:Crystalline powder, White to light beigeMolecular weight:294.40(+)-Cinchonine, 98+%, cont. up to 3% quinidine/dihydroquinidine and 3% quinine/dihydroquinine
CAS:This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C19H22N2OPurity:98+%Color and Shape:White to pale cream, Crystals or powder or crystalline powderMolecular weight:294.40(S)-Quinolin-4-yl((1S,2R,4S,5S)-5-vinylquinuclidin-2-yl)methanol
CAS:Formula:C19H22N2OPurity:85%Color and Shape:SolidMolecular weight:294.3908Cinchonine
CAS:Cinchonine (LA40221), a potent amide local anesthetic for surface use, is toxic and limited to spinal anesthesia.Formula:C19H22N2OPurity:97.62% - 99.45%Color and Shape:White Or Almost White Solid PowderMolecular weight:294.39(5-Ethenyl-1-azabicyclo[2.2.2]oct-2-yl)(quinolin-4-yl)methanol
CAS:(5-Ethenyl-1-azabicyclo[2.2.2]oct-2-yl)(quinolin-4-yl)methanolColor and Shape:White SolidMolecular weight:294.39g/molCinchonine
CAS:Stability Light Sensitive Applications Stereomeric with Cinchonidine (C441925). Antimalarial. References Litchfield, J., et al.: J. Pharm. Exp. Ther., 96, 99 (1949), Trager, W., et al.: Science, 193, 673 (1976), Panisko, D., et al.: Drugs, 39, 160 (1990), Karle, J., et al.: Antimicrob. Agents Chemother., 36, 1538 (1992),Formula:C19H22N2OColor and Shape:NeatMolecular weight:294.39Cinchonine
CAS:Cinchonine is a naturally occurring alkaloid, which is derived from the bark of the Cinchona tree. This compound is known for its antimalarial properties, functioning primarily through the inhibition of the heme polymerase enzyme in Plasmodium parasites. By interfering with the conversion of toxic heme into the non-toxic hemozoin, cinchonine effectively causes an accumulation of toxic heme within the parasite, ultimately leading to its death. Apart from its historical use in antimalarial treatment, cinchonine has applications in the synthesis of chiral compounds due to its ability to act as a chiral catalyst, providing an enantioselective environment in chemical reactions. It is also useful in scientific research for its stereochemistry and pharmacological activities. While not as commonly utilized today with modern synthetic alternatives available, it remains of scientific interest for its unique properties and mechanisms. Understanding the action of natural alkaloids like cinchonine continues to be significant in the field of medicinal chemistry and the development of new therapeutic agents.Formula:C19H22N2OPurity:Min. 95%Molecular weight:294.39 g/mol
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