CAS: 118074-07-0

Clarithromycin impurity Q is a byproduct of clarithromycin that is formed when clarithromycin reacts with ozone. Clarithromycin impurity Q has been shown to have a potential risk for the environment and wastewater treatment plants. It can be found in wastewater as an oxidized form or methylated form, depending on the extent of its degradation. Clarithromycin impurity Q is a member of the class of antibiotics and may be toxic to aquatic life. The rate of reaction between clarithromycin and ozone was found to be influenced by the concentration of both products. The kinetics were found to follow first-order kinetics at low concentrations and zero-order kinetics at high concentrations.

Lactones nesoi

Impurity Clarithromycin EP Impurity Q Applications Clarithromycin N-oxide (Clarithromycin EP Impurity Q) is an urinary metabolite of Clarithromycin (C559750), a macrolide antibiotic. References Jones, P., et al.: J. Med. Chem., 15, 631 (1972), Watanabe, Y., et al.: J. Antibiot., 46, 647 (1983), Ohmori, S., et al.: Drug Metab. Dispos., 21, 358 (1993),