CAS: 1181770-72-8

EMD638683,a novel SGK inhibitor with antihypertensive potency(with an IC50 of 3 μM).

EMD638683

3,5-Difluoro-alpha-hydroxybenzeneacetic acid 2-(2-ethyl-4-hydroxy-3-methylbenzoyl)hydrazide is a drug that inhibits the enzyme p450, which is involved in the detoxification of many drugs and xenobiotics. This drug has been shown to reduce the effects of certain drugs like cyclosporine and tacrolimus by inhibiting their metabolism. 3,5-Difluoro-alpha-hydroxybenzeneacetic acid 2-(2-ethyl-4-hydroxy-3-methylbenzoyl)hydrazide has also been shown to modulate the effects of certain drugs like acetaminophen. The drug can be used as a sensor to detect other chemicals in the body such as erythromycin, clindamycin, or ketoconazole. It may be used for termination of pregnancy and lowering blood pressure in patients